Vitamin B12 Deficiency & Pernicious Anaemia
How Treatment Variables Relate to Symptoms
Vitamin B12 use was assessed in just under 200 Pernicious Anaemia and/or Vitamin B12 Deficiency patients. Each person was asked to report as many discrete epochs of B12 use as possible, defined as periods of B12 treatment (i.e. characterized by the type of cobalamin used, frequency of use, administration route and dosage). A list of 20 symptoms were rated for severity, for each epoch entered.
Group results can be found below, showing that oral B12 is not as effective as injections and that injections work better when administered more frequently. The final published report can be found here.
If you contributed data to this study you can see your personal results here.
Biomarkers & Treatment Parameters
This study is an extension of our first survey with the Pernicious Anaemia / Vitamin B12 Deficiency community. Here we are collecting data concerning your symptoms, treatment parameters as well as medical test values from your physician. We'll be collecting data for likely a year or two and should eventually be able to make some reliable claims about how certain biomarkers of B12 deficiency (such as serum B12) relate to your symptoms. We should also be able to replicate, with stronger data, the results from the first survey which suggest oral B12 is not as effective as injections and that more frequent injections are better.
If you've been contributing to this study you can see your personal data here. Group results will not be available for quite some time yet.